This paper presents a new theory of how breast cancer metastases can be initiated by transient systemic inflammation resulting from primary surgery and also describes how a common perioperative NSAID can inhibit this process.
Current Medicinal Chemistry, 2013, 20, 00-00 1
0929-8673/13 $58.00+.00 © 2013 Bentham Science Publishers
Reduction of Breast Cancer Relapses with Perioperative Non-Steroidal
Anti-Inflammatory Drugs: New Findings and a Review
Michael Retsky1,2,*, Romano Demicheli3, William JM Hrushesky4, Patrice Forget5, Marc De Kock5,
Isaac Gukas6, Rick A Rogers1, Michael Baum7, Vikas Sukhatme8 and Jayant S Vaidya7